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KMID : 0359319980380020413
Korean Journal of Veterinary Research
1998 Volume.38 No. 2 p.413 ~ p.418
Effects of chemical restraint drugs on Doppler echocardiography in normal dogs

Abstract
Intracardiac velocities were determined and the wave-forms described for 4 flow areas of the normal canine heart following administration of chemical restraint drugs including xylazine HCl, ketamine HCl, and thiopental sodium using pulsed wave Doppler echocardiography. The result was that xylazine HCl and thiopental sodium reduced intracardiac flow velocities through mitral, tricuspid, aortic and pulmonary valves. It is also thought that precautions are required before using these drugs. Patterns of wave-forms had no changes between control and treatment groups.
Doppler echocardiography allows the clinician to determine flow velocities across the different valves and within the various chambers of the heart. It is shown that establishing normal values and those related to chemical restraint administrations and knowing what influences them should allow the clinician to non-invasively diagnose a variety of pathological cardiac conditions.
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